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Gastrointestinal
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Generic Nexium (Esomeprazole) 20 mg
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Nexium is used for treating gastroesophageal reflux disease (GERD) in patients with a history of irritation and swelling of the esophagus when medicine cannot be taken by mouth. Nexium is a proton pump inhibitor. It works by decreasing the amount of acid produced in the stomach.

Synonyms: Nexpro; Olzole; Raciper; Sompraz; Omeprazole; Prilosec; Zegerid;


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Generic Name: Esomeprazole Injection (ES-oh-MEP-ra-zole) Brand Name: Nexium
Nexium is used for:
Treating gastroesophageal reflux disease (GERD) in patients with a history of irritation and swelling of the esophagus when medicine cannot be taken by mouth. It may also be used for other conditions as determined by your doctor. Nexium is a proton pump inhibitor. It works by decreasing the amount of acid produced in the stomach.
Do NOT use Nexium if:
- you are allergic to any ingredient in Nexium or similar medicines (eg, omeprazole)
- you are taking an HIV protease inhibitor (eg, atazanavir)
Contact your doctor or health care provider right away if any of these apply to you.
Before using Nexium:
Some medical conditions may interact with Nexium . Tell your doctor or pharmacist if you have any medical conditions, especially if any of the following apply to you:
- if you are pregnant, planning to become pregnant, or are breast-feeding
- if you are taking any prescription or nonprescription medicine, herbal preparation, or dietary supplement
- if you have allergies to medicines, foods, or other substances
- if you have liver problems or stomach or bowel c cancer
Some MEDICINES MAY INTERACT with Nexium. Tell your health care provider if you are taking any other medicines, especially any of the following:
- Voriconazole because it may increase the risk of Nexium 's side effects
- Anticoagulants (eg, warfarin), cilostazol, or digoxin because the risk of their side effects may be increased by Nexium
- Azole antifungals (eg, ketoconazole), HIV protease inhibitors (eg, atazanavir), or iron because their effectiveness may be decreased by Nexium
This may not be a complete list of all interactions that may occur. Ask your health care provider if Nexium may interact with other medicines that you take. Check with your health care provider before you start, stop, or change the dose of any medicine.
How to use Nexium:
Use Nexium as directed by your doctor. Check the label on the medicine for exact dosing instructions.
- Nexium is usually given as an injection at your doctor's office, hospital, or clinic.
- Do not use Nexium if it contains particles, is cloudy or discolored, or if the vial is cracked or damaged.
- If you also take an imidazole antifungal (eg, ketoconazole), take it at least 2 hours before using Nexium.
- Keep this product, as well as syringes and needles, out of the reach of children and pets. Do not reuse needles, syringes, or other materials. Ask your health care provider how to dispose of these materials after use. Follow all local rules for disposal.
- Nexium should only be used for a short time (up to 10 days), until you are able to take medicine by mouth. Discuss any questions or concerns with your doctor.
- Continue to use Nexium even if you feel well. Do not miss any doses.
- If you miss a dose of Nexium , use it as soon as possible. If it is almost time for your next dose, skip the missed dose and go back to your regular dosing schedule. Do not use 2 doses at once.
Ask your health care provider any questions you may have about how to use Nexium.
Important safety information:
- Nexium may cause drowsiness or dizziness. These effects may be worse if you take it with alcohol or certain medicines. Use Nexium with caution. Do not drive or perform other possibly unsafe tasks until you know how you react to it.
- Contact your doctor if you have any symptoms of a bleeding ulcer, such as black, tarry stools or vomit that looks like coffee grounds; or if you experience throat pain, chest pain, severe stomach pain, or trouble swallowing.
- Nexium may interfere with certain lab tests. Be sure your doctor and lab personnel know you are using Nexium.
- Nexium should be used with caution in Asian patients; the risk of side effects may be increased in these patients.
- Nexium should be used with extreme caution in CHILDREN; safety and effectiveness in children have not been confirmed.
- PREGNANCY and BREAST-FEEDING: If you become pregnant, contact your doctor. You will need to discuss the benefits and risks of using Nexium while you are pregnant. It is not known if Nexium is found in breast milk. Do not breast-feed while using Nexium.
Possible side effects of Nexium:
All medicines may cause side effects, but many people have no, or minor, side effects. Check with your doctor if any of these most COMMON side effects persist or become bothersome:
- Constipation; diarrhea; dry mouth; gas; headache; nausea; pain, swelling, or redness at the injection site; stomach pain.
Seek medical attention right away if any of these SEVERE side effects occur:
- Severe allergic reactions (rash; hives; itching; difficulty breathing; tightness in the chest; swelling of the mouth, face, lips, or tongue; unusual hoarseness); chest pain; fast heartbeat; fever, chills, or sore throat; red, swollen, blistered, or peeling skin; unusual bruising or bleeding; unusual tiredness.
This is not a complete list of all side effects that may occur.
Proper storage of Nexium:
Nexium is usually handled and stored by a health care provider. if you are using Nexium at home, store Nexium as directed by your pharmacist or health care provider. Keep Nexium out of the reach of children and away from pets.